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1 лекарственная устойчивость микроорганизмов
[греч. mikros — маленький и лат. organismus — живое тело, живое существо]способность микроорганизмов сохранять жизнедеятельность, включая размножение, несмотря на присутствие в окружающей среде лекарственных химиопрепаратов. Л.у.м. (резистентность) отличается от толерантности микроорганизмов (см. толерантность (3)), при которой микробные клетки не гибнут в присутствии химиопрепаратов из-за уменьшенного количества аутолитических ферментов, но и не размножаются. Л.у.м. — широко распространенное явление, препятствующее лечению инфекционных болезней; наиболее изучена лекарственная устойчивость бактерий (напр., устойчивость к антибиотикам). Л.у.м. может возникать в результате способности микроорганизмов инактивировать лекарственные вещества или за счет изменения биологических мишеней, на которые действуют лекарства, вследствие мутаций в геноме.Толковый биотехнологический словарь. Русско-английский. > лекарственная устойчивость микроорганизмов
См. также в других словарях:
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Multidrug resistance — is a condition enabling a disease causing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the organism. Organisms that display multidrug resistance can be pathologic cells,… … Wikipedia
Antibiotic resistance — The ability of bacteria and other microorganisms to withstand an antibiotic to which they were once sensitive (and were once stalled or killed outright). Also called drug resistance … Medical dictionary
